We analyzed the sensitivity of a separationless immunoassay scheme using functionalized magnetic nanoparticles (MNPs) and a sensitive HTS SQUID magnetometer. The signal of a 100 μL sample at a concentration of 1 mg/mL and field of 7.5 nT was 20 mΦ0. This makes it possible for the sensitivity to be within the range of 50 ng/mL at the required time of up to 100 s per a point in the frequency spectrum
The paper provides an analysis of experimental data obtained in the study of the mechanisms of interaction of fast electron beams with flat dielectric surfaces of various materials. In addition the new experimental results on the grazing interaction of 10 keV electrons with the metallized structured surface are presented. It is shown the difference in the interaction processes of the fast electron beams with flat and structured surfaces.
We performed a sensitivity analysis for the scheme of immunoassay using functionalized magnetic nanoparticles (IPM) and sensitive HTS SQUID magnetometer. The signal from the sample (100 μ) at a concentration of 1 mg/ml in a field 7.5 nT is equal to 20 мФ$_0$. This allows the sensitivity in the range of 50 ng/ml at time cost up to 100 s to a point in frequency spectrum.