Annotation
The agent Panavir possesses versatile antiviral, anti-inflammatory, and analgesic effects, which still have not been explained at the molecular level. Here, we propose a simple physicochemical model of Panavir nanoparticles, which allows one to explain its effects by the mechanical activation of cells, including those of the immune system. Thus, there is no need for binding of the Panavir particles to any supramolecular chiral receptor for manifestation of its all known effects.
Received: 2014 July 1
Approved: 2015 January 21
PACS:
82.45.Mp Thin layers, films, monolayers, membranes
87.15.-v Biomolecules: structure and physical properties
87.17.-d Cell processes
87.15.-v Biomolecules: structure and physical properties
87.17.-d Cell processes
© 2016 Publisher M.V.Lomonosov Moscow State University
Authors
S.V. Stovbun$^1$, L.V. Yakovenko$^2$
$^1$Semenov Institute of Chemical Physics, Russian Academy of Sciences, ul. Kosygina 4, Moscow, 119991, Russia
$^2$Department of Physics, Moscow State University, Moscow, 119991, Russia
$^1$Semenov Institute of Chemical Physics, Russian Academy of Sciences, ul. Kosygina 4, Moscow, 119991, Russia
$^2$Department of Physics, Moscow State University, Moscow, 119991, Russia