Annotation
We analyzed the sensitivity of a separationless immunoassay scheme using functionalized magnetic nanoparticles (MNPs) and a sensitive HTS SQUID magnetometer. The signal of a 100 μL sample at a concentration of 1 mg/mL and field of 7.5 nT was 20 mΦ0. This makes it possible for the sensitivity to be within the range of 50 ng/mL at the required time of up to 100 s per a point in the frequency spectrum
Received: 2016 July 1
Approved: 2017 April 18
PACS:
85.25.Dq Superconducting quantum interference devices
87.83.+a Biomedical applications of nanotechnology
75.75.Jn Dynamics of magnetic nanoparticles
87.83.+a Biomedical applications of nanotechnology
75.75.Jn Dynamics of magnetic nanoparticles
© 2016 Publisher M.V.Lomonosov Moscow State University
Authors
O. Snigirev$^{1,2}$, I. Soloviev$^3$, A. Kalabukhov$^4$, M. Chukharkin$^4$
$^1$Faculty of physics, Lomonosov Moscow State University\
$^2$National Research Center Kurchatov Institute\
$^3$Skobeltsyn Institute of Nuclear Physics, Lomonosov Moscow State University\
$^4$Chalmers University of Technology, Gothenburg, Kemivagen 9, Sweden, SE 412 96
$^1$Faculty of physics, Lomonosov Moscow State University\
$^2$National Research Center Kurchatov Institute\
$^3$Skobeltsyn Institute of Nuclear Physics, Lomonosov Moscow State University\
$^4$Chalmers University of Technology, Gothenburg, Kemivagen 9, Sweden, SE 412 96