Annotation
A review of the physical laws of spatial structure formation in proteins during folding - process by which a homochiral polypeptide chain acquires a unique native configuration - is presented, including mathematical models of the process. The review materials are summarized by a new phenomenological model for the formation of hierarchies of alternating chiral structures, as well as by a new mathematical model for the formation of -helices as autowave structures. The thermodynamic aspects of folding associated with symmetry factors are discussed.
Received: 2018 December 20
Approved: 2019 August 26
PACS:
87.15.-v Biomolecules: structure and physical properties
Rissian citation:
А. Э. Сидорова, Н. Т. Левашова, Е. В. Малышко, В. А. Твердислов.
Автоволновая самоорганизация в фолдинге белков. Вестн. Моск. ун-та. Сер. 3. Физ. Астрон. 2019. № 3. С. 3.
© 2016 Publisher M.V.Lomonosov Moscow State University
Authors
A. E. Sidorovа, N. T. Levashova, E. V. Malyshko, V. A. Tverdislov
$^1$Faculty of Physics, M.V.Lomonosov Moscow State University
$^1$Faculty of Physics, M.V.Lomonosov Moscow State University