Proton transfer in catalytic center of serine proteinases (demonstrated with $\alpha$-chymotrypsin)

Dynamics of a proton has been considered in a non.stationary potential under the effect of a quasiharmonic signal, a colored noise simulating thermal fluctuations of atoms and atomic groups, and an impulse parametric excitation simulating the influence of the carbon atom in the peptide bond on the potential, wherein the proton transfer takes place. The behavior of the system has been studied with various colored noise and pulse action par8.Illeters. The wave function has been computed on the basis of the spectral method of splitting the evolution operator implemented on the cluster in the Research Computer Center of Moscow University.