Regular Article

Experimental research on fibrin clot permeability with albumin present

A.V. Nikolaev$^1$, E.I. Sinauridze$^2$, V.N. Buravtsev$^1$

Moscow University Physics Bulletin 2009. 64. N 3. P. 324

Article

Annotation

Fibrin clots are characterized by low permeability, which affects the spatial aspects of the coagulation process. Between blood plasma albumins noncovalent interactions are possible. The hypothesis that albumin accumulates in clots was examined. It was shown that albumin can not bind with fibrin clots in noticeable quantities, i.e., its presence has no impact on clot permeability neither during formation nor after-wards. During filtration at the free clot boundary a hardening zone resembling compacted clots in its permeability is formed.

Received: 2008 October 29

Approved: 2009 July 10

PACS:

87.15.-v Biomolecules: structure and physical properties
87.15.Rn Reactions and kinetics; polymerization

Authors

A.V. Nikolaev$^1$, E.I. Sinauridze$^2$, V.N. Buravtsev$^1$
$^1$Semenov Institute of Chemical Physics, ul. Kosygina 4, Moscow, 119991, Russia
$^2$National Research Center for Hematology, Russian Academy of Medical Sciences, Novyi Zykovskii pr. 4a, Moscow, 125167, Russia

Issue 3, 2009

Moscow University Physics Bulletin

Science News of the Faculty of Physics, Lomonosov Moscow State University

This new information publication, which is intended to convey to the staff, students and graduate students, faculty colleagues and partners of the main achievements of scientists and scientific information on the events in the life of university physicists.