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Formation of dipole nanoclusters in blood serum protein solutions containing europium and potassium ions

T.N. Tikhonova$^1$, G.P. Petrova$^1$, Yu.M. Petrusevich, K.V. Fedorova$^1$, V.V. Kashin$^2$

Moscow University Physics Bulletin 2011. 66. N 2. P. 190

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Annotation

Aqueous solutions of major serum proteins (albumin and g-globulin) with small concentrations of potassium and europium ions were investigated with the use of photon-correlation spectroscopy and atomicforce microscopy. The coefficients of translation diffusion, as well as the effective radiuses of the scattering particles in the solutions as a function of pH and salt concentration, were obtained. It was found that protein dipole nanoclusters form in these solutions, which was confirmed by AFM methods as well.

Received: 2010 October 25
Approved: 2011 December 14
PACS:
87.15.-v Biomolecules: structure and physical properties
87.83.+a Biomedical applications of nanotechnology
Authors
T.N. Tikhonova$^1$, G.P. Petrova$^1$, Yu.M. Petrusevich, K.V. Fedorova$^1$, V.V. Kashin$^2$
$^1$Molecular Physics Subdepartment, Physics Department, Moscow State University, Moscow, 119991, Russia
$^2$Nanocomposite Materials Laboratory, Kotel’nikov Institute of Radio Engineering and Electronics, Russian Academy of Sciences, Moscow, 125009, Russia
Issue 2, 2011

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