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Interaction of albumin and $\gamma$-globulin molecules with gold nanoparticles in water solutions

V.V. Gibizova$^1$, I.A. Sergeeva$^1$, G.P. Petrova$^1$, A.V. Priezzhev$^2$, N.G. Khlebtsov$^3$

Moscow University Physics Bulletin 2011. 66. N 5. P. 449

  • Article
Annotation

The molecular mobility of scattering particles in water solutions of albumin and $\gamma$-globulin proteins with gold nanoparticles was investigated by the dynamic light scattering method. The dependences of translation diffusion coefficients of particles at various concentrations of the solution components have been obtained. It was revealed that in a wide range of concentrations of the solution components there is no interaction of gold nanoparticles with albumin, whereas gold nanoparticles form complexes with $\gamma$-globulin molecules.

Received: 2011 May 5
Approved: 2011 November 11
PACS:
82.37.-j Single molecule kinetics
87.14.-g Biomolecules: types
87.15.-v Biomolecules: structure and physical properties
42.62.-b Laser applications
Authors
V.V. Gibizova$^1$, I.A. Sergeeva$^1$, G.P. Petrova$^1$, A.V. Priezzhev$^2$, N.G. Khlebtsov$^3$
$^1$Department of Molecular Physics, Faculty of Physics, Moscow State University, Moscow, 119991, Russia
$^2$Department of General Physics and Wave Processes, Faculty of Physics, Moscow State University, Moscow, 119991, Russia
$^3$Institute of Biochemistry and Plant and Microorganism Physiology of the Russian Academy of Sciences, 13 prosp. Entuziastov, Saratov, 410049, Russia
Issue 5, 2011

Moscow University Physics Bulletin

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